Orna Therapeutics

Orna Therapeutics is reconstructing the way diseases are treated with new technology of fully engineered circular RNA’s. They wanted their new headquarters to offer the ability to change locations, views and postures for its dynamic, informal and collaborative culture.

The new space offers a 50/50 office & lab split, covering two floors at 500 Forge in Watertown, MA. Taking cues from their scientific methodology
and brand logo, TRIA incorporated circular motifs in lighting and pops of color that serve to guide staff to different collaboration points. Natural light pours into its largest zone, the café, where employees can gather and socialize. Within the office areas, paths lead to more open support areas as well as many closed offices offering acoustical and visual privacy.

Project Location

Watertown, MA

Project Size

70,000 SF

Services

Lab Programming & Planning
Visioning

Orna Therapeutics is reconstructing the way diseases are treated with new technology of fully engineered circular RNA’s. They wanted their new headquarters to offer the ability to change locations, views and postures for its dynamic, informal and collaborative culture.

The new space offers a 50/50 office & lab split, covering two floors at 500 Forge in Watertown, MA. Taking cues from their scientific methodology and brand logo, TRIA incorporated circular motifs in lighting and pops of color that serve to guide staff to different collaboration points. Natural light pours into its largest zone, the cafe, where employees can gather and socialize. Within the office areas, paths lead to more open support areas as well as many closed offices offering acoustical and visual privacy.

Vigil Neuroscience

Vigil Neuroscience is bringing the world’s first microglia-focused therapeutics to patients who suffer from rare and neurodegenerative diseases. While transforming the lives of patients, the staff wanted a robust and focused lab and office work space but also one that promoted unity and conversation. TRIA offered a diversity of spaces that fostered collaboration and community without losing sight of the importance of acoustic privacy to allow for concentrated work.

Across from the boardroom, a 3D interactive textile board became an opportunity to fulfill the CEO’s vision of engaging staff, visitors and patients to feel the positive effects of their daily work.

The lab space includes microscope room, tissue culture room, holding/procedure room and a glass wash/autoclave room. It also
satisfies LEED equivalent requirements in a newly constructed building in Arsenal Park.

Project Location

Watertown, MA

Project Size

19,000 SF

Services

Lab Programming & Planning
Visioning

Vigil Neuroscience is bringing the world’s first microglia-focused therapeutics to patients who suffer from rare and neurodegenerative diseases. While transforming the lives of patients, the staff wanted a robust and focused lab and office work space but also one that promoted unity and conversation.

Located in Boylston Properties Arsenal Yards Development, the light filled space offers sweeping  views of the Boston skyline. TRIA offered a diversity of spaces that fostered collaboration and community without losing sight of the importance of acoustic privacy to allow for concentrated work.

Across from the boardroom, a 3D interactive textile board became an opportunity to fulfill the CEO’s vision of engaging staff, visitors and patients to feel the positive effects of their daily work. The lab space includes microscope room, tissue culture room, holding/procedure room and a glass wash/autoclave room. It also satisfies LEED equivalent requirements in a newly constructed building in Arsenal Park.

Abata Therapeutics

When Abata realized that they were outgrowing their workplace in Cambridge, they capitalized on an opportunity to move its operations to Watertown, which allowed them to plan for further growth. The new construction at Arsenal Park provided them with summer views of the treetops and winter views of the Charles River. Because Abata is translated as “quiet place of peace,” the TRIA team utilized design details with this understated brand culture. The new tranquil office features an open concept with lots of natural light, preserved moss, and organic shapes to mimic the lines in the Abata logo. The interior lab glass walls feature glazing to provide semi privacy, while the exterior lab windows share views of Arsenal Park.

Project Location

Watertown, MA

Project size

24,000 SF

Project Type

Programming & Planning
Visioning
Interior Design

When Abata realized that they were outgrowing their workplace in Cambridge, they capitalized on an opportunity to move its operations to Watertown, which allowed them to plan for further growth. The new construction at Boylston Properties Arsenal Yards development provided them with summer views of the treetops and winter views of the Charles River. Because Abata is translated as “quiet place of peace,” the TRIA team utilized design details with this understated brand culture. The new tranquil office features an open concept with lots of natural light, preserved moss, and organic shapes to mimic the lines in the Abata logo. The interior lab glass walls feature glazing to provide semi privacy, while the exterior lab windows share views of Arsenal Park.

Vertex Pharmaceuticals

Vertex Pharmaceuticals is a global biotechnology company, located in Boston’s Innovation District, that invests in scientific innovation to create transformative medicines for people with serious diseases, with multiple approved medicines that treat the underlying cause of cystic fibrosis (CF,  and has several ongoing clinical and research programs in CF.

After a complete programming and planning effort to define Vertex’s requirement and workplace strategies, TRIA provided architectural services for The Jeffrey Leiden Center One for Cell and Genetic Therapies. The process, completed throughout the pandemic, was led by our lab-focused architect, who successfully implemented over 60 building changes to the original core and shell, which was originally designed for multiple tenants.

Achieving LEED Platinum certification, this new state-of-the-art facility, a “Workplace of the Future”, features labs and manufacturing operations. For the remaining 40% of the office space, Vertex utilizes neighborhood-based office space with quick huddle areas, large and small conference rooms, a large cafeteria with room for informal company meetings, a rooftop with sweeping views of the harbor and city, a fitness room, an IT bar, coffee bar and several kitchenettes.

This project was the topic of a panel discussion at  BisNow’s March 31, 2022 Boston Life Science Summit as a Case Study, Enhancing Urban Manufacturing.  To learn more, see our Insights. 

Location

Boston, MA

Size

268,000 SF

Services

New Buildout
Lab Design
Process Architecture
Workplace Evaluation
Visioning
Programming and Planning
Renderings
Sustainable Design
Interior Design

Vertex Pharmaceuticals is a global biotechnology company, located in Boston’s Innovation District, that invests in scientific innovation to create transformative medicines for people with serious diseases, with multiple approved medicines that treat the underlying cause of cystic fibrosis (CF) and has several ongoing clinical and research programs in CF.

After a complete programming and planning effort to define Vertex’s requirements and workplace strategies, TRIA provided architectural services for The Jeffrey Leiden Center One for Cell and Genetic Therapies. The process, completed throughout the pandemic, was led by our lab-focused architect who successfully implemented changes from an original multi-tenant design to a single one.

Achieving LEED Platinum certification, this new state-of-the-art facility, a “Workplace of the Future”, features labs and manufacturing operations. For the remaining 40% of the office space, Vertex utilizes neighborhood-based office space with quick huddle areas, large and small conference rooms, a large cafeteria with room for informal company meetings, a rooftop with sweeping views of the harbor and city, a fitness room, an IT bar, coffee bar and several kitchenettes.

This project was the topic of a panel discussion at  BisNow’s March 31, 2022 Boston Life Science Summit as a Case Study, Enhancing Urban Manufacturing.  To learn more, see our Insights. 

Abcam

TRIA provided design services for Abcam’s new lab and office fit-out located in Waltham, MA. Through extensive visioning with the Abcam team, their new Waltham headquarters was designed to promote an open and collaborative team environment. Abcam’s science is on display throughout the office and café. Using glass-paned walls to separate the spaces preserves their vision of transparency. The open office features several huddle rooms and conference spaces, promoting a collaborative atmosphere that offers flexibility and connectivity. Lounge spaces and amenity spaces with ample seating encourage officewide communication, as well as areas for the Abcam team to recharge.

The new headquarters features a clean, minimal color palette, vibrantly accented by various pieces of furniture. Walls and window-film featuring sleek, geometric patterns offer visual interest, while also providing a visual denotation between office and amenity spaces.

LOCATION

Waltham, MA

SIZE

70,000 SF

SERVICES

Tenant Improvements
Workplace Evaluation
Visioning
Interior Design
Visioning
Programming and Planning
Lab Design

Abcam identifies, develops, and provides high-quality biological reagents and tools essential in a wide range of fields and applications, including drug discovery, diagnostics, and basic research. Abcam’s mission is to serve life scientists so they can achieve their mission, faster.

Through extensive visioning with the Abcam team, their new Waltham headquarters was designed to promote an open and collaborative team environment. Abcam’s science is on display throughout the office and café. Using glass-paned walls to separate the spaces preserves their vision of transparency. The open office features several huddle rooms and conference spaces, promoting a collaborative atmosphere that offers flexibility and connectivity. Lounge spaces and amenity spaces with ample seating encourage officewide communication, as well as areas for the Abcam team to recharge.

The new headquarters features a clean, minimal color palette, vibrantly accented by various pieces of furniture. Walls and window film featuring sleek, geometric patterns offer visual interest while providing a visible denotation between the office and amenity spaces.

Arranta Bio

Arranta Bio provides novel solutions to clients for advanced therapy process development and manufacturing.  Their expertise and ability to provide end-to-end solutions helps guide therapeutic products through the clinical journey to the commercial.

In their new Watertown facility, Arranta Bio needed a state-of-the-art facility flexibly engineered as a multi-product facility to accommodate a range of manufacturing processes across single-use technology platforms.

TRIA provided design services for the multi-phase renovation and fit-out of a former warehouse space into this cGMP development and manufacturing facility. Designed for full process stages along with lyophilization and capsule filling, all new process equipment and building utility equipment were installed along with new clean utility generation. The facility is configured to allow for expansion to larger scale production as demand increases.

The rear portion building features a 9,000 SF research and development lab suite and a 6,000 SF quality control lab suite on the first floor, with conference rooms, huddle rooms and a large forum/kitchen. The front portion of the building serves as the lobby/reception area and it includes lounge seating, kitchenette, conference rooms, offices, and huddle rooms for use by visitors to the facility. Reflecting Arranta Bio’s brand, the look is modern with navy and teal accent colors used throughout the space, helping to create a holistic, cohesive design between lab and office. In addition, windows were added on the second floor to bring natural light into the offices and storefront windows were added to the front office.

Location

Watertown, MA

Size

80,000 SF

SERVICES

Building Repositioning
Visioning
Programming and Planning
Interior Design
Partial New Construction

Arranta Bio provides novel solutions to clients for advanced therapy process development and manufacturing.  Their expertise and ability to provide end-to-end solutions helps guide therapeutic products through the clinical journey to the commercial.

In their new Watertown facility, Arranta Bio needed a state-of-the-art facility flexibly engineered as a multi-product facility to accommodate a range of manufacturing processes across single-use technology platforms.

TRIA provided design services for the multi-phase renovation and fit-out of a former warehouse space into this cGMP development and manufacturing facility. Designed for full process stages along with lyophilization and capsule filling, all new process equipment and building utility equipment were installed along with new clean utility generation. The facility is configured to allow for expansion to larger scale production as demand increases.

The rear portion building features a 9,000 SF research and development lab suite and a 6,000 SF quality control lab suite on the first floor, with conference rooms, huddle rooms and a large forum/kitchen. The front portion of the building serves as the lobby/reception area and it includes lounge seating, kitchenette, conference rooms, offices, and huddle rooms for use by visitors to the facility. Reflecting Arranta Bio’s brand, the look is modern with navy and teal accent colors used throughout the space, helping to create a holistic, cohesive design between lab and office. In addition, windows were added on the second floor to bring natural light into the offices and storefront windows were added to the front office.

Foghorn Therapeutics

Foghorn Therapeutics, a biotechnology research company, is pioneering the discovery and development of a new class of medicines targeting genetically determined dependencies within the chromatin regulatory system.

Foghorn Therapeutics and the project team set out to transform three levels at 500 Technology Square into a sanctum of innovation. The building’s core acts as a center point of circulation divergence. Subtly angled walls, ceilings, and floors wrap the building’s core creating a continuous path that allows users to seamlessly transition from one space to another. Formal and informal collaboration spaces along this path allow for natural interactions between co-workers.

Levels six through eight of this lab and office renovation have merged with a staircase, creating easier opportunities for staff to connect and collaborate. Hefty steel beams brace the waffle slab construction and reveal a three-story-looking glass.

Level six includes an extensive chemistry lab, featuring an open ceiling concept where mechanical ductwork remains exposed as a critical aesthetic. Office areas here include “neighborhoods” of workstations and dedicated collaboration spaces. Level seven greets guests with an inviting reception area, while also providing an extensive cafe that doubles as a company-wide assembly space. The office neighborhoods converge at this central hub, creating opportunities for informal gatherings. Level seven also includes an extensive set of biology lab suites. The core circulation follows along to create a connection from the lab to the office. Finally, level eight offers additional opportunities for office and lab spaces to admix. A large board room acts as a hub for business.

location

Cambridge, MA

size

44,000 SF

Services

Tenant Improvements
Workplace Evaluation
Interior Design
Lab Design
Visioning
Planning and Programming

Foghorn Therapeutics, a biotechnology research company, is pioneering the discovery and development of a new class of medicines targeting genetically determined dependencies within the chromatin regulatory system. 

The project team set out to transform three levels at 500 Technology Square into a sanctum of innovation. The building’s core acts as a center point of circulation divergence. Subtly angled walls, ceilings, and floors wrap the building’s core creating a continuous path that allows users to seamlessly transition from one space to another. Formal and informal collaboration spaces along this path allow for natural interactions between co-workers.

Levels six through eight of this lab and office renovation have merged with a staircase, creating easier opportunities for staff to connect for collaborations. Hefty steel beams brace the waffle slab construction and reveal a three-story-looking glass.

Level six includes an extensive chemistry lab, featuring an open ceiling concept where mechanical ductwork remains exposed as a critical aesthetic. Office areas here include “neighborhoods” of workstations and dedicated collaboration spaces. Level seven greets guests with an inviting reception area, while also providing an extensive cafe that doubles as a company-wide assembly space. The office neighborhoods converge at this central hub, creating opportunities for informal gatherings. Level seven also includes an extensive set of biology lab suites. The core circulation follows along to create a connection from the lab to the office. Finally, level eight offers additional opportunities for office and lab spaces to admix. A large board room acts as a hub for business.

Glympse Bio

Glympse Bio, a biotechnology company developing revolutionary technology to diagnose and monitor disease, needed a new headquarters.  After completing test fits, TRIA provided architectural and engineering services for one floor consisting of 60% laboratory and 40% office and amenity spaces.

During visioning, it was determined that Glympse Bio employees were looking for collaborative spaces. An efficient, economical design was achieved by creating multi-functional spaces, such as a flexible cafe that can double as a meeting space for large or small groups. Additional features include open benching, writing surfaces, and glass partitions. The outcome is a modern and inspiring workspace for Glympse Bio employees to call home.

LOCATION

Cambridge, MA

SIZE

22,000 SF

SERVICES

Tenant Improvements
Interior Design
Lab Design
Visioning
Programming and Planning

Glympse Bio, a biotechnology company developing revolutionary technology to diagnose and monitor disease, needed a new headquarters.  After completing test fits, TRIA provided architectural and engineering services for one floor consisting of 60% laboratory and 40% office and amenity spaces.

During visioning, it was determined that Glympse Bio employees were looking for collaborative spaces. An efficient, economical design was achieved by creating multi-functional spaces, such as a flexible cafe that can double as a meeting space for large or small groups. Additional features include open benching, writing surfaces, and glass partitions. The outcome is a modern and inspiring workspace for Glympse Bio employees to call home.

Platelet Biogenesis

Platelet Bio, a preclinical-stage biotechnology company pioneering an entirely new platform of allogeneic cell therapies based on platelet biology, asked TRIA to create a culture-centric and functional design for its new lab and office space on one floor.

The existing building’s floor-to-ceiling windows provide ample sunlight with commanding views of the neighborhood. Periodic glass walls between the lab and office spaces provide a collective visual connection, allowing for transparency amongst coworkers and potential clients. An exceptional design feature is the automated glass wall between the boardroom and adjacent café, which can disappear above the ceiling to create one large meeting space for all-hands gatherings. This element supports wider firm cohesion and is a notable addition to the office, which speaks to Platelet’s unique culture and identity. TRIA extended this detailed approach to the laboratories, where great care was taken to enhance lab safety. Personal protective equipment, eye wash and safety showers are clearly visible; biosafety cabinets, refrigerators, fume hoods and autoclaves are located for safety and energy efficiency. Lastly, hands-free entries to tissue culture rooms open powered doors, reducing contamination.

LOCATION

Watertown, MA

SIZE

17,500 SF

SERVICES

Tenant Improvements
Branding
Workplace Evaluation
Interior Design
Lab Design
Visioning
Programming and Planning

Platelet Bio, a preclinical-stage biotechnology company pioneering an entirely new platform of allogeneic cell therapies based on platelet biology, asked TRIA to create a culture-centric and functional design for its new lab and office space on one floor.

The existing building’s floor-to-ceiling windows provide ample sunlight with commanding views of the neighborhood. Periodic glass walls between the lab and office spaces provide a collective visual connection, allowing for transparency amongst coworkers and potential clients. An exceptional design feature is the automated glass wall between the boardroom and adjacent café, which can disappear above the ceiling to create one large meeting space for all-hands gatherings. This element supports wider firm cohesion and is a notable addition to the office, which speaks to Platelet’s unique culture and identity. TRIA extended this detailed approach to the laboratories, where great care was taken to enhance lab safety. Personal protective equipment, eye wash and safety showers are clearly visible; biosafety cabinets, refrigerators, fume hoods and autoclaves are located for safety and energy efficiency. Lastly, hands-free entries to tissue culture rooms open powered doors, reducing contamination.

Biogen 6-6

Biogen, a biotech company, discovers, develops, and delivers innovative therapies worldwide for people living with serious neurological and neurodegenerative diseases. The global organization, headquartered in Cambridge, MA is also home to its research operations.

The renovation of Building 6, Floor 6, a mixed lab and office space accommodates multiple groups within Biogen’s Research & Development Organization. The floor was converted to support biologics laboratories, with a shared lab services space and open office, including collaboration and huddle spaces, copy centers, mail rooms, and approximately 10,000 square feet of lab area. The wet lab space consists of open lab, lab support, tissue culture, and cold storage. TRIA designed the space to maintain a strong visual connection between lab and office, both in design and transparency, allowing the staff to remain connected regardless of the day’s requirements.

LOCATION

Cambridge, MA

SIZE

18,000 SF

SERVIcES

Tenant Improvements
Lab Design
Interior Design
Planning and Programming

Biogen, a biotech company, discovers, develops, and delivers innovative therapies worldwide for people living with serious neurological and neurodegenerative diseases. The global organization, headquartered in Cambridge, MA is also home to its research operations.

The renovation of Building 6, Floor 6, a mixed lab and office space accommodates multiple groups within Biogen’s Research & Development Organization. The floor was converted to support biologics laboratories, with a shared lab services space and open office, including collaboration and huddle spaces, copy centers, mail rooms, and approximately 10,000 square feet of lab area. The wet lab space consists of open lab, lab support, tissue culture, and cold storage. TRIA designed the space to maintain a strong visual connection between lab and office, both in design and transparency, allowing the staff to remain connected regardless of the day’s requirements.