Tour ElevateBio’s BaseCamp Facility

Date

April 15, 2022

ElevateBio’s Waltham BaseCamp facility

Join ElevateBio and ISPE for an evening of facility tours and panel discussions with industry experts. Tour the award winning facility designed by TRIA and learn more about site selection, design, construction and the challenges of achieving operational readiness and delivering life-saving therapies.

Learn about the perspectives and strategies of bringing a new multi-modal facility on-line from Mike Paglia, COO, ElevateBio BaseCamp; new process technologies, throughput modelling and designing for flexibility from Emily Heffernan, US Director, New Process Technology, DPS Group; and the challenges that abound with site selection and leveraging local and state incentive programs from Bob Coughlin, Managing Director, JLL.

Event Details

Wednesday, June 8, 2022
5:00PM – 7:30PM
ElevateBio BaseCamp
200 Smith Street, Waltham, MA 02451

For more information and to register for the event click here

ElevateBio Basecamp 

First-of-its-kind cell and gene therapy manufacturing facility recognized for operational excellence.

TRIA provided architecture and design services for the interior fit-out of a raw warehouse space into a state-of-the art cGMP development and manufacturing facility for novel therapeutic technologies. Designed to feel like a “basecamp” – a physical foundation point for the incremental climb in the company’s growth, the client’s new facility features a collaborative open plan office and amenities that promote interaction, and provide flexible production suites for GMP manufacturing, laboratories, and a range of supporting utility and warehouse areas. The facility produces viral vector, cell therapy, gene therapy, and regenerative medicine for clinical purposes.

About TRIA

TRIA is a full-service architecture firm that values client relationships above all. The firm’s principal-driven approach puts our leadership team at the table with client decision-makers, working together to envision success, solve problems and deliver exceptional results. Our lab design and corporate interiors teams strive to learn every client’s unique DNA, and by doing so, we create efficient and energizing spaces that reflect a company’s culture and foster innovation. At TRIA, we design spaces that enable business success and advance new discoveries – in the lab, around the office, and beyond. Visit us on the web at https://tria.design and connect with us on LinkedIn.

Solutions to help Speed-to-Market Drug Researchers

Date

February 16, 2022

Author

Edwin Hargrave

Staff Bio

Edwin Hargrave
Header

Lab renderings of speculative suites,
located at Berkeley Investments, 200 Exchange, Malden, MA.

Science and Technology Planner lends expert design considerations for a new market of Spec Research Suites

The race to develop new drugs has developers—and TRIA—offering innovative solutions when state of the art lab space is hard to find.

When Berkeley Investments did a comprehensive redevelopment of 200 Exchange in Malden, they collaborated with TRIA to help develop speculative lab suites (spec suites), attracting tenants in the market who need to act quickly, and are looking for more of a “move-in-ready” option. Spec suites provide the unique ability to house their offices, R&D/lab & GMPc facilities under one roof with little or minimal customization.

What makes them unique?

Associate Principal Edwin Hargrave, AIA, Director of Integrated Design, Science and Technology, shares his expertise.

With a traditional planning project we work with end users to design customized or bespoke labs that are often highly specialized.  With Spec Suites, the design process creates an opportunity with Life Sciences property developers to understand their goals and parameters for the project. We then relying upon our vast experience in the Boston marketplace to identify best design solutions for the geographic location and the target market.

When working with developers to create these “move-in ready” spec suites, we also consult our comprehensive database of programming and planning metrics to provide the most appropriate spaces and lab services for the widest possible range of potential tenants. This approach results in a nearly turn-key lab space that is ready for tenants who are making the jump from incubator space or spinning off new strategic research initiatives. Having a near turn-key lab allows tenants to continue to research activities or in the case of start-ups begin them immediately without interruptions to their operations or timelines.

Spec Suites offer their own challenges in design, mainly because they have smaller footprints to reduce rents and thus have less square footage. Flexibility and efficiency are key, and we recommend utilizing a 10’ to 11’ planning module for all lab spaces, and the use of moveable laboratory benching.

Here are several key considerations:

  • When fitting out the suites, we recommend furnishing the major pieces of laboratory equipment for the most commonly used spaces but deferring others to tenants. For example, install one or more fume hoods in the open lab, and two to four biosafety cabinets in the tissue culture (TC) room along with adequate floor space for stacking incubators. Plan another lab support room with similar dimensions to serve as a second TC room should a tenant desire it, but don’t furnish the BSC’s. Further, consider sizing another lab support room to serve as a glasswash/autoclave room, along with the necessary MEP infrastructure, but leave the purchase of the specialized equipment to the tenant.
  • Materials management spaces (consumables, freezer farms, chemistry and bio waste) should be located near a secondary entrance directly into the laboratory suite, preferably with direct access to a freight elevator.
  • The basic complement of distributed laboratory utilities—normal and emergency power, data, vacuum and compressed air—should be centrally distributed to all lab spaces using an overhead service panel system to eliminate fixed wall mounted devices that limit flexibility.
  • Laboratory HVAC systems should be designed with 100% outside air (non-recirculating) to ensure compatibility with the safety protocols for life sciences research. The exhaust system should have capacity for additional point of use exhausts (snorkels, benchtop workstations) in the lab areas, beyond the provided fume hoods.

Being experts in lab design and having proven experience designing every lab element allows TRIA to work seamlessly with developers to design highly functional and attractive spec suites, increasing available lab space in the market and allowing tenants to move in quicker, without interruptions to their ongoing research and development.

“In today’s heated market for lab space, speed to occupancy is critically important to drug researchers, who are often in a race to advance their research and can’t afford the disruptions of a drawn out space search or a lengthy construction project,” said Dan McGrath, Senior Vice President and Director of Asset Management for Berkeley. “Constructing spec suites provides tenants with move-in-ready space, but developers need to make sure the space they are delivering meets the needs of today’s lab tenants. At 200 Exchange Street, we counted on the expertise of lab planners and designers at TRIA to ensure our spec suites were flexible, functional, and met the needs of the lab users in the market.”

TRIA Completes Headquarters for Biopharmaceutical Company Affinivax

Date

July 15, 2021

Pioneer in development of a novel class of vaccines leverages new space to support scientific research mission

BOSTON – 6/10/21 – TRIA, a partner-led architecture firm with a focus on designing unique spaces for science, technology and corporate clients, announced today that it has completed the design of a new 50,000 SF headquarters for Affinivax, Inc., a clinical stage biopharmaceutical company pioneering the development of a novel class of vaccines with its . Moving locations from shared laboratory space at LabCentral to a leased third floor suite at 301 Binney Street in Kendall Square, Cambridge, Mass., Affinivax’s new headquarters features a mix of office, lab, amenity, and collaboration areas. In a synergistic manner between Affinivax and the project team, the space was specially designed to support the company’s scientific research mission and growth while reflecting the company’s collaborative culture.

Affinivax is pioneering the development of a novel class of vaccines designed to induce a broad and robust protective immune response to both disease-relevant polysaccharides and disease-relevant proteins in a single vaccine. Affinivax designs each of its vaccine candidates to optimize the protective immune response to one or both of these antigens utilizing the distinctive plug-and-play nature of its proprietary MAPS™ platform technology, presenting the potential opportunity to make a significant step forward in addressing major healthcare challenges posed by novel and resistant infectious diseases. Affinivax was founded in 2014 with a seed investment from the Bill & Melinda Gates Foundation and an exclusive license to the MAPS technology from Boston Children’s Hospital.

“We couldn’t have asked for a better design partner,” said Ann Straight, Director of Human Resources at Affinivax. “TRIA took the time to walk us through their design process and helped us see the potential in this unique space. It was truly a collaborative process between the Affinivax, TRIA, and entire project team. We are so pleased with the results and the fact that this space is customized for Affinivax.”

The existing core of the building houses a sizeable mechanical space, resulting in a large circular floor plan that created a challenge for the team when it came to connecting the office and lab spaces. TRIA addressed this design challenge by designing a central corridor which circles around the existing MEP building core, establishing a path from office to lab while serving as the main circulation route through the lab zone. This “path” is highlighted through the use of special flooring, lighting and ceilings, helping to guide visitors and employees through the space.

From the moment of stepping off the elevator into the main reception area, the use of glass provides extensive visibility into the labs, putting Affinivax’s cutting-edge research on display. Additionally, the transparency opens up the floor plan and draws natural light throughout Affinivax, creating a visual connection between the core and the exterior. Open offices and collaborative spaces with seating are located along the perimeter to take advantage of natural light, conference huddle spaces are situated in the middle, and private offices on the interior of the space. Using a variety of huddle areas in both the lab and office, as well as a central café and meeting space, the design encourages teamwork and communication, while giving employees flexibility and versatility throughout their workday. An environmental graphic designer created a branding wall and timeline of the company’s history which is displayed on wedge-like wall fins, pointing the way from the main entrance to the café and central meeting hub.

Project team members include:

  • Architect/Interior Design: TRIA
  • Construction Manager: The Richmond Group
  • Owner’s Rep: Hereva
  • Mechanical, Electrical, and Plumbing Engineer: Vanderweil
  • Structural Engineer: McNamara Salvia
  • Environmental Graphic Design: Kayte Muse Creative
  • Code Consultant: Code Red
  • Furniture : Total Office Interiors

About TRIA

TRIA is a full-service architecture firm that values client relationships above all. The firm’s principal-driven approach puts our leadership team at the table with client decision-makers, working together to envision success, solve problems and deliver exceptional results. Our lab design and corporate interiors teams strive to learn every client’s unique DNA, and by doing so, we create efficient and energizing spaces that reflect a company’s culture and foster innovation. At TRIA, we design spaces that enable business success and advance new discoveries – in the lab, around the office, and beyond. Visit us on the web at https://tria.design and connect with us on Twitter, LinkedIn, and Facebook.

DPS Group and TRIA Congratulate ElevateBio’s BaseCamp on ISPE Facility of the Year Award

Date

May 6, 2021

First-of-its-kind cell and gene therapy manufacturing facility recognized for operational excellence

BOSTON – May 6, 2021 – DPS Group, a privately-owned, global engineering, procurement, construction management and validation (EPCMV) firm serving high-tech process industries, and TRIA, a partner-led architecture firm with a focus on designing unique spaces for science and technology and corporate clients, congratulate ElevateBio’s BaseCamp for being selected as the 2021 Facility of the Year Awards (FOYA) category winner for operational excellence by the International Society for Pharmaceutical Engineering (ISPE). ISPE’s Facility of the Year Awards is an annual program that recognizes state-of-the-art projects utilizing new, innovative technologies to improve the quality of products, reduce the cost of producing high-quality medicines, and demonstrate advances in project delivery. Winners in the operational excellence category exemplify the application of modern management techniques aimed to improve operating efficiencies, promote excellent quality, consistency and yield competitive cost of goods from existing and new facilities, processes, and manufacturing operations.

“At ElevateBio, we are reimagining the way cell and gene therapies and regenerative medicines are discovered, developed, and manufactured,” said Mitchell Finer, Ph.D., President, ElevateBio BaseCamp. “An industry-leading facility, ElevateBio BaseCamp is central to that vision. We’ve built an incredible facility  and brought together a team of experts in immunology, regenerative medicine, and cell and gene therapies to help our portfolio companies and strategic partners get the process right from the start.“

ElevateBio selected DPS and its design affiliate TRIA to provide their synergistic services for engineering design, architecture, consulting, and interior design services for the fit-out of a raw warehouse space into a state-of-the art cGMP development and manufacturing facility for novel therapeutic technologies. Designed to feel like a “BaseCamp”, a physical foundation point for the incremental climb in the company’s growth, ElevateBio’s new facility features a collaborative open plan office and amenities that promote interaction, and provide flexible production suites for GMP manufacturing, laboratories, and a range of supporting utility and warehouse areas.

“We thank ISPE for recognizing ElevateBio as a FOYA category winner; the incredible team at ElevateBio for executing on our vision; and our partners at DPS Group and TRIA for delivering the facility we are so proud of,” added Mario Miele, Vice President of Facilities and Engineering at ElevateBio.

After evaluating and advising ElevateBio about potential locations for a retrofit, DPS and ElevateBio designed the GMP manufacturing space for this project. The design incorporates separate suites for viral vector production and cell therapy processing and was informed by modeling numerous process equipment scenarios for typical upstream and downstream processing of CGTs. DPS, TRIA, and ElevateBio worked collaboratively to design the GMP manufacturing spaces to be flexible enough to accommodate research, process development, and manufacturing for different technologies and cell and gene therapy products.  DPS services included feasibility study, schematic design, design development, construction documents, construction administration, and CQV support.

TRIA’s design for ElevateBio’s open office and lab space embraced the ceiling heights, abundant natural light, exposed steel beams, and other original features of the former postal service distribution center. The BaseCamp concept blends a comfortable, nature-based color palette with the industrial aesthetic of the existing building, using a light-toned wooden ceiling lattice to highlight the exposed ductwork and help to scale the expansive ceilings of 16 to 24 feet in areas. Upon entry to reception, the space flows from the open office with café and huddle spaces, to the glass-walled labs that promote transparency for employees, and finally to the GMP manufacturing area. DPS and TRIA collaborated on the architectural design and MEP engineering of the lab suite for quality control testing and process development, ensuring a continuity of design and transparency between the office, lab, and manufacturing spaces. TRIA services included feasibility study, schematic design, design development, construction documents, and construction administration.

Other project team members include The Richmond Group (Construction Management); McNamara/Salvia (Engineering); Thompson Consulting, Inc. (Engineering), New England Controls (Automation/Controls); and 42° North Solutions (Commissioning, Qualification, & Validation).

About ElevateBio BaseCamp

With more than 140,000 square feet of space, ElevateBio BaseCamp includes current Good Manufacturing Practice (cGMP) manufacturing suites, analytics, and quality control (QC) laboratories, and protein engineering, virology, and immunology labs, all with state-of-the-art laboratory automation. BaseCamp was designed to support diverse gene and cell regenerative therapy products, with manufacturing suites that have flexible floor plans for cGMP manufacturing. The facility has autologous, allogeneic, and regenerative medicine cell products such as induced pluripotent stem cells, or iPSC, and viral vector manufacturing capabilities. Additionally, the BaseCamp cGMP manufacturing suite environment, equipment, and processes are monitored by validated and integrated computer systems.

BaseCamp creates true end-to-end solutions in multi-modal facilities to deliver across a very wide mix of product requirements. Leveraging digitalization platforms, BaseCamp can rapidly deploy solutions for portfolio companies and partnerships utilizing repeatable processes and delivering on time at required quality thresholds, providing a future proof platform.

In addition to the world-class facility, BaseCamp also has world-class staff with expertise in developing and manufacturing immunotherapies, regenerative medicine products, in vivo viral-based therapies, and other cell and gene therapies.

About ElevateBio

ElevateBio is a cell and gene therapy technology company built to power the development of transformative cell and gene therapies today and for many decades to come. The company has assembled industry-leading talent, built world-class facilities, and integrated diverse technology platforms necessary for rapid innovation and commercialization of cell, gene, and regenerative therapies. The company has built an initial technology stack, including gene editing, induced pluripotent stem cells, and protein, viral, and cellular engineering. At the center of the business model is ElevateBio BaseCamp, a centralized R&D and manufacturing company that offers research and development (R&D), process development (PD), and Current Good Manufacturing Practice (CGMP) manufacturing capabilities. The company is focused on increasing long-term collaborations with industry partners while also continuing to develop its own highly innovative cell and gene therapies. ElevateBio’s team of scientists, drug developers, and company builders are redefining what it means to be a technology company in the world of drug development, blurring the line between technology and healthcare.

ElevateBio is headquartered in Cambridge, Mass, with ElevateBio BaseCamp located in Waltham, Mass. For more information, visit us at www.elevate.bio, or follow Elevate on LinkedIn, Twitter, or Instagram.

About DPS Group

DPS Group is a global engineering, consulting and project management company, serving high-tech industries around the world. DPS delivers services for clients across the complete engineering and construction value chain including feasibility studies, concepts, consulting, architecture, engineering, procurement, construction management, commissioning, qualification and validation as well as contingent staffing solutions.

DPS applies its extensive process engineering expertise built over 45 years, as well as significant Lean construction experience to assist clients in high-end process sectors such as pharmaceuticals, biotech, and semiconductors to deliver manufacturing facilities speedily, safely, and cost effectively. What sets the firm apart is the partnerships it builds with clients through a fundamental understanding of their businesses and its own agility, flexibility, original thinking, and high-caliber people.

DPS has grown substantially in recent years and now employs more than 2,000 people in 16 offices and on client sites in Ireland, U.K., Netherlands, Belgium, Sweden, Switzerland, Israel, Singapore, Saudi Arabia, and the United States. For more information, visit www.dpsgroupglobal.com.

About TRIA

TRIA is a full-service architecture firm that values client relationships above all. The firm’s principal-driven approach puts our leadership team at the table with client decision-makers, working together to envision success, solve problems and deliver exceptional results. Our lab design and corporate interiors teams strive to learn every client’s unique DNA, and by doing so, we create efficient and energizing spaces that reflect a company’s culture and foster innovation. At TRIA, we design spaces that enable business success and advance new discoveries – in the lab, around the office, and beyond. Visit us on the web at https://tria.design and connect with us on Twitter, LinkedIn, and Facebook.

About the ISPE Facility of the Year Awards Program

Established in 2004, The Facility of the Year Awards (FOYA) recognize state-of-the-art projects utilizing new, innovative technologies to improve the quality of products, reduce the cost of producing high-quality medicines, and demonstrate advances in project delivery. The FOYA program provides a platform for the pharmaceutical science and manufacturing industry to showcase its accomplishments in facility design, construction, and operation, while sharing the development of new applications of technology and cutting-edge approaches. Visit ISPE.org/FOYA for more information.

DPS and TRIA Complete First Phase for Arranta Bio’s Manufacturing Facility

Date

December 15, 2020

BOSTON – December 15, 2020 – DPS Group, a privately-owned, global engineering, procurement, construction management, and validation (EPCMV) firm serving high-tech process industries, and TRIA, a principal-led architecture firm with a focus on designing unique spaces for science, technology, and corporate clients, are pleased to announce the completion of the first phase of the 80,000 SF Arranta Bio Manufacturing Facility. Working in partnership with construction manager DC Beane, DPS and TRIA provided architectural, interior design, engineering, and project management services for a new manufacturing facility for microbiome therapeutics located at 650 Pleasant Street in Watertown, Mass. This multi-phase project will be mechanically complete and ready for full occupancy by the end of 2020.

Founded in 2019 with the acquisition of a 10-year old microbiome service provider, Arranta Bio is a contract development and manufacturing organization (CDMO) specifically established to focus on serving companies seeking to develop and commercialize therapeutics targeting the human microbiome. The microbiome refers to the genetic material of literally trillions of microbes – bacteria, fungi, protozoa, and viruses – that live inside and on the human body. Scientists have called it the second genome and over the last decade, there has been a rapid acceleration in scientific understanding of the composition and functions of the gut microbiota. Today, around 200 companies are focused on understanding the human microbiome and its linkage to areas including infectious diseases and oncology, with the goal of identifying therapeutic targets.

“Our goal is to be the leader in our sector. We are doing this with over a decade of experience making live biopharmaceuticals,” said Mark Bamforth, founder, president and CEO of Arranta Bio. “This new manufacturing facility gives us the ability to better support our clients as they continue their work to develop life-enhancing medicine and to bring these through licensure. The combined team of DPS and TRIA – and their deep understanding of our industry – have enabled us to create a facility which will help our clients develop and manufacture promising new Microbiome-based therapies.”

Arranta Bio selected DPS and its design affiliate TRIA to provide design services for the renovation and fit-out of a former warehouse space into a cGMP development and manufacturing facility. Among the many challenges was converting the warehouse building into a state-of-the-art manufacturing space which has the capacity and flexibility to handle a broad range of drug production for Arranta Bio clients. Designed for full process stages along with lyophilization and capsule filling, all new process equipment and building utility equipment were installed along with new clean utility generation. The facility is configured to allow for expansion to larger scale production as demand increases. Current maximum fermentation capacity is 2 x 2000 L, with a total of 13 cGMP suites.  The Arranta Bio facility design allows for agility in process configurations, incorporating single use equipment, strategically located utility panels, and a centralized Vaporized Hydrogen Peroxide (VHP) routed to each room to streamline changeover decontaminations.

“The future of microbiome-based therapy is certainly exciting,” said Aaron Cowley, chief scientific officer for Arranta Bio. “We are uniquely positioned within the microbiome space to facilitate the entire life cycle from bench to market. This new facility allows us to have the technical team that performs basic scientific work on hand to support and troubleshoot a product launch, resulting in shorter timelines and reduced cost and risk.”

When complete, the rear portion building will feature a 9,000 SF research and development (R&D) lab  suite and a 6,000 SF quality control (QC) lab suite on the first floor, with conference rooms, huddle rooms and a large forum/kitchen above on the second floor.  Coordinating the MEP requirements to the first floor lab areas was a another significant challenge with the existing building.  Located right off the parking lot, the front portion of the building will serve as the lobby/reception area and it will include lounge seating, kitchenette, conference rooms, offices, and huddle rooms for use by visitors to the facility. Taking a cue from Arranta Bio’s branding, the look is clean and modern with navy and teal accent colors used throughout the space, helping to create a holistic, cohesive design between lab and office. Open ceiling, patterned carpet, and warm wood toned luxury vinyl tile form a welcoming environment for employees and visitors alike. Upgrades to the exterior included new cladding, exterior lighting, and repairs to the roof. In addition, windows were added on the second floor to bring natural light into the offices and storefront windows were added to the front office.

The project team on Arranta Bio’s manufacturing facility include:

  • Owner: Arranta Bio
  • Construction Manager: DC Beane and Associates Construction Company
  • Architect: TRIA
  • Process Engineer: DPS Group
  • Process Architect: DPS Group
  • MEP Engineers: DPS Group
  • Site and Civil Engineer: VHB
  • Structural Engineers: Goldstein/Milano

About DPS Group

DPS Group is a global engineering, consulting and project management company, serving high-tech industries around the world. DPS delivers services for clients across the complete engineering and construction value chain including feasibility studies, concepts, consulting, architecture, engineering, procurement, construction management, commissioning, qualification and validation, as well as contingent staffing solutions.

DPS applies its extensive process engineering expertise built over 45 years, as well as significant Lean construction experience to assist clients in high-end process sectors such as pharmaceuticals, biotech and semiconductors to deliver manufacturing facilities speedily, safely and cost effectively. What sets the firm apart are the partnerships it builds with clients through a fundamental understanding of their businesses and its own agility, flexibility, original thinking and high-caliber people.

DPS has grown substantially in recent years and now employs more than 1,850 people in 16 offices and on client sites in Ireland, U.K., Netherlands, Belgium, Sweden, Switzerland, Israel, Singapore, Saudi Arabia, and the United States. For more information, visit www.dpsgroupglobal.com.

About TRIA

TRIA is a full-service architecture firm that values client relationships above all. The firm’s principal-driven approach puts our leadership team at the table with client decision-makers, working together to envision success, solve problems and deliver exceptional results. Our lab design and corporate interiors teams strive to learn every client’s unique DNA, and by doing so, we create efficient and energizing spaces that reflect a company’s culture and foster innovation. At TRIA, we design spaces that enable business success and advance new discoveries – in the lab, around the office, and beyond. Visit us on the web at https://tria.design and connect with us on Twitter, LinkedIn, and Facebook.

The Flexible Design of Post COVID-19 Workplaces

Date

October 7, 2020

Author

Lucianna Scordo, Melissa Kennedy & Neli Ialamov

Staff Bio

This pandemic has surely changed the way of the world. It has also significantly impacted the way we work. So, what is to come for workplace design?

With the spread of COVID-19, a dramatic shift has taken place in the way we work and interact with our colleagues and clients. As we continue to learn more about the virus and methods of prevention, we look to the future to see what lessons can be drawn from this pandemic, and how our offices can be better prepared in the years to come. Even in a post-COVID-19 world, when temperatures start to drop and we enter cold and flu season, it will be more important than ever for employees not only to be safe from the spread of germs, but also FEEL safe in an office environment.

So, where is corporate interior design heading? Here are some of our top predictions:

Flexible design still reigns

The pandemic has shown us that companies benefit from remaining flexible and fluid in unprecedented times, both within the office space and when addressing unforeseen challenges. While established offices have quickly pivoted to implement social distancing and rigorous cleaning practices, future office spaces can rely on pre-meditated design choices to mitigate the risks of future viruses, from large-scale pandemics to the common flu. This will ultimately lead to safer, more agile environments where both employees and clients feel safe doing business.

Open office may get even more open

While at first glance, one might assume that open collaboration spaces would be less desirable in future designs to properly maintain social distancing, we believe the opposite to be the case. Enclosed areas may be phased out to support the introduction of an advanced open office, which prioritizes proper circulation and air filtration. An open space allows employees to remain socially distanced, rather than being confined to an enclosed office or meeting room. In addition, defined circulation paths let employees move throughout the space in a manner that promotes one-way travel, to limit close interaction, and circumvents encroaching on others’ workspaces. Obviously, with this true open office plan, challenges will be presented, such as noise considerations.

Bring fresh air into the space

As previously mentioned, air circulation is something that is now and will continue to be an important element of office design. This design development will lead to close collaboration between the architect and engineers, as we work to find the most efficient method to consistently reintroduce and circulate fresh air into the office.

Surfaces needs to be cleanable

As has already started to be the case, design will pivot to the use of materials that are easily cleaned, such as plexiglass and wipeable fabric. Even when this pandemic is over, we still see the cleanability of shared surfaces to be an important consideration of design.

 Consider touchless items

Automated mechanisms will be integrated into the office design, with the proliferation of touchless technology for high-traffic objects such as trash cans, doors, and soap dispensers. The reduction of touchable shared surfaces will limit the spread of germs amongst staff and visitors, and lead to less clean-up overall.

Organized PPE

Just as there are personal protective equipment (PPE) stations in lab spaces, we envision such stations becoming more prevalent in offices to mitigate the risk of the spread of germs. These stations may even become an element of the design in the space, creating a functional yet elegant solution to distribute hand sanitizer, masks, and gloves. Cleanliness has always had its place in design, but we now see opportunities to expand the design with simple and cost-effective changes.

Our office spaces will adapt and evolve to best serve both business and employee needs. However, as it is difficult to foresee every challenge the future may hold, one thing remains certain: flexible and agile spaces that allow us to pivot with our changing needs will continue to be at the core of every design.

Event Spotlight: 2020 IIDA New England Design Awards

Date

October 2, 2020

Author

Lucianna Scordo & Edwin Hargrave

Staff Bio

The 13th Annual IIDA New England Design Awards took place on the 16th of September and was an excellent example of how industry events can still be professional and entertaining in a time of social distancing. You could see truly how much thought and effort the committee put into organizing the awards show. And while we did not get to enjoy seeing our industry friends face-to-face, we were still able to appreciate some of the beautiful designs our colleagues have created over the past year.

This year had a record number of entries, so to streamline the event, only the top three finalists in each category were featured. As always, student entries kicked off the show with talented and creative conceptual renderings, showing a promising and exciting future for the world of design. Professional entries included categories such as Education, Community & Culture, Healthcare, Hospitality, and, of course, Best in Show. All featured entries were stunning spaces that took our breath away. Year after year, this event continues to impress and enthrall, as it helps to showcase the beauty of Boston and New England design, and gives credit to the talented teams that work on these projects.

TRIA was overjoyed to have two projects nominated as a finalist and winner in the Research Lab Category. PureTech Health was a runner up, and Generation Bio won the category! For Generation Bio, judges highlighted an effective plan, the use of transparency between lab and office, and a modest yet confident design. A holistic and integrated approach between lab and office to promote collaboration and discovery is a fundamental characteristic of our design philosophy, and we are glad that this concept shined through in our design. One of the ways we incorporated continuity was through the use of glass walls, allowing science to be on display. Collaboration was another key component of the design, which was highlighted by incorporating neighborhood seating and central collaboration zones of technology-enabled conference rooms.

A huge thank you to the IIDA New England Design Awards Committee for putting on another wonderful event. We are already looking forward to next year!

Before you go, check out the Electronic Event Booklet and ‘Winners Look Book’!

Hot Property: Vertex Seaport Offices

Date

August 24, 2020

Author

Steve Adams - Banker & Tradesman Staff

This article initially appeared in Banker & Tradesman on August 23, 2020.

What: Vertex Cell and Genetic Therapies center
Where: 6 Tide St., Boston
Owner: Related Beal
Built: 2020-2021 

Boston-based architecture firm Tria has been selected to design Vertex Pharmaceuticals’ new cell and genetic therapies center in Boston’s Seaport District. 

The 268,000-square-foot facility at 6 Tide St. will contain large molecule R&D labs, clinical-scale manufacturing operations, analytical and microbiology labs, general office space, support operations, bulk gas storage and staff amenities. 

In addition to achieving LEED certification, the manufacturing operations will meet cGMP (current good manufacturing practices) requirements and ISO classifications. TRIA will be responsible for lab, office, and amenity design, while working closely with the entire project team. 

Members of the project team include process architect and engineer Jacobs, BR+A Consulting Engineers, McNamara Salvia Structural Engineers, code consultant Cosentini Associates, LEED consultant Thornton Tomasetti and Kyle Zick Landscape Architecture. 

They Said It: 

“TRIA is thrilled to be working alongside the Vertex project team to design this new facility for Vertex Cell and Genetic Therapies. We are proud to be supporting Vertex and their mission to bring these cutting-edge therapies to patients.”
— TRIA Managing Principal Sherwood Butler 

Vertex Pharmaceuticals Selects TRIA to Design Laboratory and Office for New 268,000 SF VCGT Research Site

Date

July 16, 2020

Lobby Rendering

State-of-the-art facility to be located in Innovation Square in Boston’s Seaport

BOSTON – TRIA, a principal-led architecture firm with a focus on designing unique workspaces for science, technology, and corporate clients, announced today that it is designing a new cell and genetic therapies research site in the Boston area for Vertex Pharmaceuticals, Inc. (Nasdaq: VRTX), a global biotechnology company. The Vertex Cell and Genetic Therapies site will house the company’s research, development, and clinical manufacturing activities for cell and genetic therapies – two rapidly emerging therapeutic modalities with the potential to treat—and even cure—several of the diseases Vertex is focused on. TRIA was selected to provide architectural services for the design and build-out of laboratory, office, and amenity spaces for Vertex’s newly constructed 268,000 SF research site.

TRIA Managing Principal Sherwood Butler said, “TRIA is thrilled to be working alongside the Vertex project team to design this new facility for Vertex Cell and Genetic Therapies. We are proud to be supporting Vertex and their mission to bring these cutting-edge therapies to patients.”

This new state-of-the-art facility will include large molecule R&D labs, clinical-scale manufacturing operations, analytical and microbiology labs, general office space, support operations, bulk gas storage, and staff amenities. In addition to achieving LEED certification, the manufacturing operations will meet cGMP requirements and ISO classifications. TRIA will be responsible for lab, office, and amenity design, while working closely with the entire project team. TRIA will implement their “form follows culture” and holistic design approach for laboratory, office, and amenity design, to reflect Vertex’s unique workplace culture.

The Vertex Cell and Genetic Therapies (VCGT) project team includes:

  • Process Architect/Engineer: Jacobs
  • MEP/FP Engineer: BR+A Consulting Engineers
  • Structural Engineer: McNamara Salvia Structural Engineers
  • Code Consultant: Cosentini Associates
  • LEED Consulting: Thornton Tomasetti
  • Landscape Architecture: Kyle Zick Landscape Architecture, Inc.

About TRIA

TRIA is a full-service architecture firm that values client relationships above all. The firm’s principal-driven approach puts our leadership team at the table with client decision-makers, working together to envision success, solve problems and deliver exceptional results. Our lab design and corporate interiors teams strive to learn every client’s unique DNA, and by doing so, we create efficient and energizing spaces that reflect a company’s culture and foster innovation. At TRIA, we design spaces that enable business success and advance new discoveries – in the lab, around the office, and beyond. Visit us on the web at https://tria.design and connect with us on Twitter, LinkedIn, and Facebook.

Hot Property: Platelet BioGenesis HQ

Date

May 26, 2020

Author

Steve Adams - Banker & Tradesman Staff

This article initially appeared in Banker & Tradesman on May 24, 2020.

What: Platelet BioGenesis headquarters
Where: 65 Grove St., Watertown
Built: 2020
Owner: BioMed Realty 

 Housed in a former mill building, the design makes full use of floor-to-ceiling windows as the office and lab spaces snake along the perimeter. 

Architects TRIA, along with developer BioMed Realty and contractor PIDC Construction, provided expedited design and construction management services for the $5.4 million project, enabling Platelet BioGenesis to move into the 17,500-square-foot facility in just 18 weeks. The space offers modular and flexible lab areas which were designed specifically to enhance safety. 

BioMed Realty acquired the 120,000-square-foot office-lab building for $62.5 million in 2017. 

They Said It: 

“Platelet BioGenesis has always prided itself on its employee cohesion and teamwork. The new space at 65 Grove St. in Watertown offers plenty of transparency and space for employees to gather and discuss new ways for the company to move forward. Overall, it is an elegant industrial design tailored for productivity and success.”
— Lucianna Lucarelli Scordo, Director of Integrated Design, Interiors and Associate Principal, TRIA