Work Category v2: Manufacturing

Vertex Pharmaceuticals

Vertex Pharmaceuticals is a global biotechnology company, located in Boston’s Innovation District, that invests in scientific innovation to create transformative medicines for people with serious diseases, with multiple approved medicines that treat the underlying cause of cystic fibrosis (CF,  and has several ongoing clinical and research programs in CF.

After a complete programming and planning effort to define Vertex’s requirement and workplace strategies, TRIA provided architectural services for The Jeffrey Leiden Center One for Cell and Genetic Therapies. The process, completed throughout the pandemic, was led by our lab-focused architect, who successfully implemented over 60 building changes to the original core and shell, which was originally designed for multiple tenants.

Achieving LEED Platinum certification, this new state-of-the-art facility, a “Workplace of the Future”, features labs and manufacturing operations. For the remaining 40% of the office space, Vertex utilizes neighborhood-based office space with quick huddle areas, large and small conference rooms, a large cafeteria with room for informal company meetings, a rooftop with sweeping views of the harbor and city, a fitness room, an IT bar, coffee bar and several kitchenettes.

This project was the topic of a panel discussion at  BisNow’s March 31, 2022 Boston Life Science Summit as a Case Study, Enhancing Urban Manufacturing.  To learn more, see our Insights. 

Location

Boston, MA

Size

268,000 SF

Services

New Buildout
Lab Design
Process Architecture
Workplace Evaluation
Visioning
Programming and Planning
Renderings
Sustainable Design
Interior Design

Vertex Pharmaceuticals is a global biotechnology company, located in Boston’s Innovation District, that invests in scientific innovation to create transformative medicines for people with serious diseases, with multiple approved medicines that treat the underlying cause of cystic fibrosis (CF) and has several ongoing clinical and research programs in CF.

After a complete programming and planning effort to define Vertex’s requirements and workplace strategies, TRIA provided architectural services for The Jeffrey Leiden Center One for Cell and Genetic Therapies. The process, completed throughout the pandemic, was led by our lab-focused architect who successfully implemented changes from an original multi-tenant design to a single one.

Achieving LEED Platinum certification, this new state-of-the-art facility, a “Workplace of the Future”, features labs and manufacturing operations. For the remaining 40% of the office space, Vertex utilizes neighborhood-based office space with quick huddle areas, large and small conference rooms, a large cafeteria with room for informal company meetings, a rooftop with sweeping views of the harbor and city, a fitness room, an IT bar, coffee bar and several kitchenettes.

This project was the topic of a panel discussion at  BisNow’s March 31, 2022 Boston Life Science Summit as a Case Study, Enhancing Urban Manufacturing.  To learn more, see our Insights. 

BXP – 103 CityPoint

BXP is a developer, owner, and manager of premier workplaces with a mission to envision, develop, and manage exceptional properties that enhance client success, strengthen communities, and advance opportunity. For its seventh property located within a one-mile radius along Rte. 128, BXP wanted to create a destination where all operational aspects of research and development are integrated under one roof, moving away from the traditional separation of manufacturing. This speculative building aims to reshape corporate culture for science and technology tenants, energizing its workforce and accelerating growth.

For innovators who value speed-to-market, 103 CityPoint, LEED Silver-certified, was meticulously designed for adaptability. It can accommodate office, lab, and cGMP spaces for single or multiple tenants. The building’s four-story exterior is a testament to the innovative spirit that lies within, showcasing a blend of rigid geometry, translucent glass, and captivating lighting. At night, its façade becomes a dynamic light canvas with over 700 feet of color-changing LEDs. allowing customized displays to celebrate holidays, support local organizations, or add vibrancy to the community that has become a prominent urban edge submarket.

Notably, the lab and office floors provide column-free floor plates, 50-ft. clear structural spans, 16-ft. floor-to-floor heights, and a façade designed around ideal lab modules, providing the utmost flexibility for a tenant’s design. Additionally, the 25,000+ SF cGMP area offers a double-height shell space to accommodate many needs.

The interior design of 103 CityPoint seamlessly blends the modern lines of its exterior with a fresh, vibrant, and elegant aesthetic. The lobby and café are inviting spaces that foster connection, featuring biophilic design elements such as an illuminated green wall adorned with moss framed in white and smoked glass accents. These elements not only enhance the space’s appeal but also promote well-being, creating a harmonious environment that is sure to inspire potential lessees.

The project began with a detailed study before proceeding with base services.  For more information, click here to see our Insights.

LOCATION

Waltham, MA

SIZE

113,000 SF

services

New Construction
Process Architecture
Sustainable Design
Lab Design
Speculative Design
Interior Design

BXP is a developer, owner, and manager of premier workplaces with a mission to envision, develop, and manage exceptional properties that enhance client success, strengthen communities, and advance opportunity. For its seventh property located within a one-mile radius along Rte. 128, BXP wanted to create a destination where all operational aspects of research and development are integrated under one roof, moving away from the traditional separation of manufacturing. This speculative building aims to reshape corporate culture for science and technology tenants, energizing its workforce and accelerating growth.

For innovators who value speed-to-market, 103 CityPoint, LEED Silver-certified, was meticulously designed for adaptability. It can accommodate office, lab, and cGMP spaces for single or multiple tenants. The building’s four-story exterior is a testament to the innovative spirit that lies within, showcasing a blend of rigid geometry, translucent glass, and captivating lighting. At night, its façade becomes a dynamic light canvas with over 700 feet of color-changing LEDs. allowing customized displays to celebrate holidays, support local organizations, or add vibrancy to the community that has become a prominent urban edge submarket.

Notably, the lab and office floors provide column-free floor plates, 50-ft. clear structural spans, 16-ft. floor-to-floor heights, and a façade designed around ideal lab modules, providing the utmost flexibility for a tenant’s design. Additionally, the 25,000+ SF cGMP area offers a double-height shell space to accommodate many needs.

The interior design of 103 CityPoint seamlessly blends the modern lines of its exterior with a fresh, vibrant, and elegant aesthetic. The lobby and café are inviting spaces that foster connection, featuring biophilic design elements such as an illuminated green wall adorned with moss framed in white and smoked glass accents. These elements not only enhance the space’s appeal but also promote well-being, creating a harmonious environment that is sure to inspire potential lessees.

The project began with a detailed study before proceeding with base services.  For more information, click here to see our Insights.

ElevateBio

2021 ISPE Award Winner for Operational Excellence!

ElevateBio BaseCamp houses a wide range of technologies, expertise, operations, processes, and GMP manufacturing under one roof, so its partners can accelerate the development of life-transforming cell and gene therapies, wherever they are in the product life cycle.

TRIA provided architecture and design services for the interior fit-out of a raw warehouse space into a state-of-the art cGMP development and manufacturing facility for novel therapeutic technologies. Designed to feel like a “basecamp” – a physical foundation point for the incremental climb in the company’s growth, the client’s new facility features a collaborative open plan office and amenities that promote interaction, and provide flexible production suites for GMP manufacturing, laboratories, and a range of supporting utility and warehouse areas. The facility produces viral vector, cell therapy, gene therapy, and regenerative medicine for clinical purposes.

Location

Waltham, MA

Project Size

115,000 SF

SERVICES

Tenant Improvements
Workplace Evaluation
Visioning
Planning and Programming
Interior Design
Lab Design
Process Architecture
Renderings

2021 ISPE Award Winner for Operational Excellence!

ElevateBio BaseCamp houses a wide range of technologies, expertise, operations, processes, and GMP manufacturing under one roof, so its partners can accelerate the development of life-transforming cell and gene therapies, wherever they are in the product life cycle.

TRIA provided architecture and design services for the interior fit-out of a raw warehouse space into a state-of-the art cGMP development and manufacturing facility for novel therapeutic technologies. Designed to feel like a “basecamp” – a physical foundation point for the incremental climb in the company’s growth, the client’s new facility features a collaborative open plan office and amenities that promote interaction, and provide flexible production suites for GMP manufacturing, laboratories, and a range of supporting utility and warehouse areas. The facility produces viral vector, cell therapy, gene therapy, and regenerative medicine for clinical purposes.

Integra LifeSciences

TRIA provided full architectural services for the relocation of this medical device client’s office and manufacturing facility. Phase I consisted of the office renovation, which was design focused, while remaining budget conscious. Branding throughout the space was a key component. For instance, a unique element in the lobby was a branding wall that displayed the client’s products.

Other important design elements were natural lighting (13 skylights were incorporated throughout the space) and collaboration zones. A central maple corridor runs throughout the space, and off the corridor are several different areas where employees can hold impromptu meetings. In addition, the cafe is large enough to hold “town hall” meetings with all employees now and with future growth.

The space also includes a full cross-fit training facility, a special request from employees.

TRIA completed Phase II in 2019, which includes cleanroom, R&D, manufacturing, shipping/receiving, and warehousing space.

  • Location
    Mansfield, MA

Project Size

112,550  SF

Services

Tenant Improvements
Interior Design
Process Architecture
Workplace Evaluation

TRIA provided full architectural services for the relocation of this medical device client’s office and manufacturing facility. Phase I consisted of the office renovation, which was design focused, while remaining budget conscious. Branding throughout the space was a key component. For instance, a unique element in the lobby was a branding wall that displayed the client’s products.

Other important design elements were natural lighting (13 skylights were incorporated throughout the space) and collaboration zones. A central maple corridor runs throughout the space, and off the corridor are several different areas where employees can hold impromptu meetings. In addition, the cafe is large enough to hold “town hall” meetings with all employees now and with future growth.

The space also includes a full cross-fit training facility, a special request from employees.

TRIA completed Phase II in 2019, which includes cleanroom, R&D, manufacturing, shipping/receiving, and warehousing space.

Entegris

TRIA designed the renovation for this 80,000 SF high-tech manufacturing and R&D facility for filtration media technologies and proprietary, innovative low-temperature coating technologies. The design was focused around a circular track-like corridor, with open office and collaboration areas. The build-out also included approximately 6,000 SF of cleanrooms, along with an advanced manufacturing facility. Furniture, finishes, and colors for the space were carefully chosen to align with the client’s pre-established facility standards.

Sherwood Butler was Managing Principal of this project at Perkins+Will where this project was completed.

Location

Bedford, MA

Size

80,000 SF

SERVICES

Tenant Improvements
Process Architecture
Lab Design
Interior Design

TRIA designed the renovation for this 80,000 SF high-tech manufacturing and R&D facility for filtration media technologies and proprietary, innovative low-temperature coating technologies. The design was focused around a circular track-like corridor, with open office and collaboration areas. The build-out also included approximately 6,000 SF of cleanrooms, along with an advanced manufacturing facility. Furniture, finishes, and colors for the space were carefully chosen to align with the client’s pre-established facility standards.

Sherwood Butler was Managing Principal of this project at Perkins+Will where this project was completed.

Moderna Therapeutics

2019 ISPE Award Winner for Facility of the Future 

TRIA provided architectural services for Moderna Therapeutics’ new $110 million, 200,000 SF GMP mRNA clinical manufacturing facility. TRIA designed clinical labs, offices, employee facilities, and a conference center. Construction of the new facility completed in mid-2018. and functions for all manufacturing activities at the site, from raw material production to active pharmaceutical ingredients (APIs), formulation, filling and finish.

DPS provided full architectural and engineering design for Moderna’s Norwood facility and also provided construction management oversight, commissioning, qualification & validation, and procurement services.

Location

Norwood, MA

Size

200,000 SF

SERVICES

Tenant Improvements
Process Architecture
Interior Design
Lab Design
Planning and Programming
Visioning

2019 ISPE Award Winner for Facility of the Future 

TRIA provided architectural services for Moderna Therapeutics’ new $110 million, 200,000 SF GMP mRNA clinical manufacturing facility. TRIA designed clinical labs, offices, employee facilities, and a conference center. Construction of the new facility completed in mid-2018. and functions for all manufacturing activities at the site, from raw material production to active pharmaceutical ingredients (APIs), formulation, filling and finish.

DPS provided full architectural and engineering design for Moderna’s Norwood facility and also provided construction management oversight, commissioning, qualification & validation, and procurement services.