Chris Graul

Senior Lab Programmer/Planner

Chris brings over two decades of experience in the pharmaceutical industry to TRIA’s lab planning and programming team. He has worked extensively as an in-vivo pharmacologist with cross-therapeutic drug discovery and early non-clinical development experience, including rare disease and fragile animal model knowledge.  As a former associate director of laboratory operations, Chris brings the ability to lead, coordinate, and manage activities from a problem-solver perspective. He sets an example of collaboration and precision as the cornerstones of execution.

Technical skills include therapeutic areas such as – CNS, GI, Pain, Metabolic Diseases, Cardiovascular, Oncology, Inflammation, and Respiratory. In-vivo Modeling experience in – Compound administration, CNS administration, Compound formulation, Efficacy studies, Pharmacokinetic studies, Toxicokinetic studies, Nuclear imaging/biodistribution, ADME, Tissue resection and Micro-resection, Survival surgery, and Vascular casting for CT acquisition.

Education

  • University of Rhode Island, Bachelor of Science, Aquaculture and Fisheries Biology; Marine Affairs minor
  • Harvard University, Extension School, Biological Science graduate coursework
  • University of Massachusetts, Environmental, Coastal and Science program, graduate coursework

certifications

  • AALAS Laboratory Animal Technician

publications

  • Gastrointestinal pain: Unraveling a novel endogenous pathway through uroguanylin/guanylate cyclase-C/cGMP activation. Silos-Santiago, Inmaculada; Hannig, Gerhard; Eutamene, Helene; Ustinova, Elena E.; Bernier, Sylvie G.; Ge, Pei; Graul, Christopher; Jacobson, Sarah; Jin, Hong; Liong, Elaine; et al Pain (2013), 154(9), 1820-1830
  • Discovery and Characterization of a Potent Interleukin-6 Binding Peptide with Neutralizing Activity In Vivo Sheila Ranganath, Ashok Bhandari, Nicole Avitahl-Curtis, Jaimee McMahon, Derek Wachtel, Jenny Zhang, Christopher Leithheiser, Guang Liu, Tran Tran, Herodion Celino, Jenny Tobin, Joon Jung, Hong Zhao, Katie E. Glen, Christopher Graul, Aleish Griffin, et al. PLOS one (2015), DOI:10.1371/journal.pone.0141330